Constipation is a commonly experienced problem and a significant source of discomfort and distress. The 2018 European Society of Medical Oncology (ESMO) updates guidelines for the diagnosis, assessment and management of constipation in advanced cancer. A recommendation for the use of peripherally acting mu-opioid receptor antagonists (PAMORAS) is made.
Larkin, N. I. et al. 2018. ESMO Clinical Practice Guidelines: Diagnosis, assessment and management of constipation in advanced cancer. Annals of Oncology 29 (4) 111-125.
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